A Single Amino Acid Change in Rabies Virus Glycoprotein Increases Virus Spread and Enhances Virus Pathogenicity

Several rabies virus (RV) vaccine strains containing an aspartic acid (Asp) or glutamic acid (Glu) instead of an arginine (Arg) at position 333 of the RV glycoprotein (G) are apathogenic for immunocompetent mice even after intracranial inoculation. However, we previously showed that the nonpathogeni...

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Hlavní autoři: Faber, Milosz, Faber, Marie-Luise, Papaneri, Amy, Bette, Michael, Weihe, Eberhard, Dietzschold, Bernhard, Schnell, Matthias J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280225/
https://ncbi.nlm.nih.gov/pubmed/16254349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.14141-14148.2005
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