Vaccination with Plasmid DNA Encoding TSA/LmSTI1 Leishmanial Fusion Proteins Confers Protection against Leishmania major Infection in Susceptible BALB/c Mice

We have recently shown that a cocktail containing two leishmanial recombinant antigens (LmSTI1 and TSA) and interleukin-12 (IL-12) as an adjuvant induces solid protection in both a murine and a nonhuman primate model of cutaneous leishmaniasis. However, because IL-12 is difficult to prepare, is expe...

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Autors principals: Campos-Neto, A., Webb, J. R., Greeson, K., Coler, R. N., Skeiky, Y. A. W., Reed, S. G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC128002/
https://ncbi.nlm.nih.gov/pubmed/12010969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.6.2828-2836.2002
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