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Role of Interleukin-18 in Host Defense against Disseminated Candida albicans Infection

In mice injected intravenously with Candida albicans, administration of anti-interleukin-18 (IL-18) antibodies increased the yeast load in the kidneys. There was no effect on the organ load with Candida when gamma interferon (IFN-γ)-deficient mice were treated with anti-IL-18 antibodies, suggesting...

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Pubblicato in:Infect Immun
Autori principali: Stuyt, Rogier J. L., Netea, Mihai G., Verschueren, Ineke, Fantuzzi, Giamila, Dinarello, Charles A., Van der Meer, Jos W. M., Kullberg, Bart Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127971/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12011026/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.6.3284-3286.2002
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