A Lipid Core Peptide Construct Containing a Conserved Region Determinant of the Group A Streptococcal M Protein Elicits Heterologous Opsonic Antibodies

The study reported here investigated the immunogenicity and protective potential of a lipid core peptide (LCP) construct containing a conserved region determinant of M protein, defined as peptide J8. Parenteral immunization of mice with LCP-J8 led to the induction of high-titer serum immunoglobulin...

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Главные авторы: Olive, Colleen, Batzloff, Michael R., Horváth, Anikó, Wong, Allan, Clair, Timothy, Yarwood, Penny, Toth, Istvan, Good, Michael F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2002
Предметы:
Microbial Immunity and Vaccines
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC127950/
https://ncbi.nlm.nih.gov/pubmed/11953422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2734-2738.2002
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