A possible mechanism of glycolytic impairment after adenosine triphosphate deplection in the perfused rat heart.

1. When the heart is deprived of substrate and O2 for a long period, the ATP content falls to very low levels, with associated changes in ADP and AMP content, and a fall in intracellular pH. 2. These changes appear sufficient to block the hexokinase reaction, outweighing the normal mechanisms contro...

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Autores principales: Grinwald, P M, Hearse, D J, Segal, M B
Formato: Artigo
Lenguaje:Inglês
Publicado: 1980
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1279402/
https://ncbi.nlm.nih.gov/pubmed/7411435
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