Mucosal Tolerance to a Bacterial Superantigen Indicates a Novel Pathway To Prevent Toxic Shock

Enterotoxins with superantigenic properties secreted during systemic Staphylococcus aureus infection are responsible for toxic shock. We show that intranasal administration of staphylococcal enterotoxin A (SEA), but not a recombinant SEA lacking superantigenic activity, protected mice against lethal...

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Publié dans:	Infect Immun
Auteurs principaux:	Collins, L. Vincent, Eriksson, Kristina, Ulrich, Robert G., Tarkowski, Andrej
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2002
Sujets:	Host Response and Inflammation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11953361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.5.2282-2287.2002
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