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Role of Pneumococcal Surface Protein C in Nasopharyngeal Carriage and Pneumonia and Its Ability To Elicit Protection against Carriage of Streptococcus pneumoniae

Previous studies suggested that PspC is important in adherence and colonization within the nasopharynx. In this study, we conducted mutational studies to further identify the role PspC plays in the pathogenesis of pneumococci. pspC and/or pspA was insertionally inactivated in a serotype 2 Streptococ...

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Autori principali: Balachandran, Priya, Brooks-Walter, Alexis, Virolainen-Julkunen, Anni, Hollingshead, Susan K., Briles, David E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC127914/
https://ncbi.nlm.nih.gov/pubmed/11953392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2526-2534.2002
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