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Activation and inhibition of calcium-dependent histamine secretion by ATP ions applied to rat mast cells.

1. The concentration dependence on ATP of mast cell histamine secretion in the presence of various concentrations of Mg2+ and Ca2+ confirms that the agonist form of ATP is the free form of ATP (ATP(free) not bound to divalent cations, i.e. ATP4-. It induces 50% activation at about 1.2 microM, maxima...

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Dettagli Bibliografici
Autori principali: Cockcroft, S, Gomperts, B D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1979
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1279075/
https://ncbi.nlm.nih.gov/pubmed/93638
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