Induction of Protective Immunity to Listeria monocytogenes by Immunization with Plasmid DNA Expressing a Helper T-Cell Epitope That Replaces the Class II-Associated Invariant Chain Peptide of the Invariant Chain

Listeria epitope-specific helper T (Th) cells were able to be primed and induced in vivo by immunization with a plasmid carrying an invariant chain (Ii) gene whose class II-associated invariant chain peptide (CLIP) region was replaced by a Listeria Th epitope. Immunization of C3H/He mice with an Ii-...

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Détails bibliographiques
Auteurs principaux: Nagata, Toshi, Aoshi, Taiki, Suzuki, Mina, Uchijima, Masato, Kim, Yeung-Hyen, Yang, Zhibo, Koide, Yukio
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Microbial Immunity and Vaccines
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC127905/
https://ncbi.nlm.nih.gov/pubmed/11953411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2676-2680.2002
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