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Intravaginal and Intranasal Immunizations Are Equally Effective in Inducing Vaginal Antibodies and Conferring Protection against Vaginal Candidiasis

Oophorectomized, estrogen-treated rats were immunized by the intravaginal or intranasal route with a mannoprotein extract (MP) or secreted aspartyl proteinases (Sap) of Candida albicans, with or without cholera toxin as a mucosal adjuvant. Both routes of immunization were equally effective in (i) in...

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Bibliographic Details
Main Authors: De Bernardis, Flavia, Boccanera, Maria, Adriani, Daniela, Girolamo, Antonietta, Cassone, Antonio
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC127899/
https://ncbi.nlm.nih.gov/pubmed/11953420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2725-2729.2002
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