Carcinoembryonic Antigen Family Receptor Recognition by Gonococcal Opa Proteins Requires Distinct Combinations of Hypervariable Opa Protein Domains

Neisserial Opa proteins function as a family of adhesins that bind heparan sulfate proteoglycan (HSPG) or carcinoembryonic antigen family (CEACAM) receptors on human host cells. In order to define the CEACAM binding domain on Opa proteins, we tested the binding properties of a series of gonococcal (...

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Detalhes bibliográficos
Main Authors: Bos, Martine P., Kao, David, Hogan, Daniel M., Grant, Christopher C. R., Belland, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127850/
https://ncbi.nlm.nih.gov/pubmed/11895933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.4.1715-1723.2002
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