Lactoferrin Inhibits the Lipopolysaccharide-Induced Expression and Proteoglycan-Binding Ability of Interleukin-8 in Human Endothelial Cells

Interleukin-8 (IL-8), a C-X-C chemokine bound to endothelium proteoglycans, initiates the activation and selective recruitment of leukocytes at inflammatory foci. We demonstrate that human lactoferrin, an antimicrobial lipopolysaccharide (LPS)-binding protein, decreases both IL-8 mRNA and protein ex...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Elass, Elisabeth, Masson, Maryse, Mazurier, Joël, Legrand, Dominique
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Host Response and Inflammation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127826/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11895948/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.4.1860-1866.2002
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