Role of Osteopontin in Murine Lyme Arthritis and Host Defense against Borrelia burgdorferi

Several genetic loci in the mouse have been identified that regulate the severity of Lyme arthritis. The region of chromosome 5 including the osteopontin (OPN) gene (Opn) has been identified in intercross populations of C3H/HeN × C57BL/6 and C3H/HeJ × BALB/cAnN mice. OPN is of particular interest as...

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Main Authors: Potter, Melissa R., Rittling, Susan R., Denhardt, David T., Roper, Randall J., Weis, John H., Teuscher, Cory, Weis, Janis J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC127811/
https://ncbi.nlm.nih.gov/pubmed/11854223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1372-1381.2002
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