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Virulence of Streptococcus pneumoniae: PsaA Mutants Are Hypersensitive to Oxidative Stress

psaA encodes a 37-kDa pneumococcal lipoprotein which is part of an ABC Mn(II) transport complex. Streptococcus pneumoniae D39 psaA mutants have previously been shown to be significantly less virulent than wild-type D39, but the mechanism underlying the attenuation has not been resolved. In this stud...

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Autors principals: Tseng, Hsing-Ju, McEwan, Alastair G., Paton, James C., Jennings, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC127802/
https://ncbi.nlm.nih.gov/pubmed/11854257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1635-1639.2002
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