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Will Investments in Large-Scale Prospective Cohorts and Biobanks Limit Our Ability to Discover Weaker, Less Common Genetic and Environmental Contributors to Complex Diseases?
Increasing the size of prospective cohorts and biobanks is one approach to discovering previously unknown contributors to complex diseases, but it may come at the price of concealing contributors that are less common across all the participants in those larger studies and of limiting hypothesis gene...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Institute of Environmental Health Sciences
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1277853/ https://ncbi.nlm.nih.gov/pubmed/15687047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.7343 |
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