Penicillium marneffei Causes Osteopontin-Mediated Production of Interleukin-12 by Peripheral Blood Mononuclear Cells

We investigated the role of osteopontin (OPN) in interleukin-12 (IL-12) production from peripheral blood mononuclear cells (PBMCs) stimulated with Penicillium marneffei. Kinetic studies showed that OPN synthesis preceded that of IL-12 at both mRNA and protein levels when PBMCs were cocultured with P...

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Bibliographic Details
Main Authors: Koguchi, Yoshinobu, Kawakami, Kazuyoshi, Kon, Shigeyuki, Segawa, Tatsuya, Maeda, Masahiro, Uede, Toshimitsu, Saito, Atsushi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC127744/
https://ncbi.nlm.nih.gov/pubmed/11854181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1042-1048.2002
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