The caspase-3 cleavage product of the plasma membrane Ca(2+)-ATPase 4b is activated and appropriately targeted

The calmodulin-activated transporter hPMCA4 (human plasma membrane Ca(2+)-ATPase isoform 4) is a target for cleavage by caspase-3 during apoptosis. We have demonstrated that caspase-3 generates a 120 kDa fragment of this pump which lacks the complete autoinhibitory sequence [Paszty, Verma, Padanyi,...

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Detalhes bibliográficos
Main Authors: Pászty, Katalin, Antalffy, Géza, Penheiter, Alan R., Homolya, László, Padányi, Rita, Iliás, Attila, Filoteo, Adelaida G., Penniston, John T., Enyedi, Ágnes
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276970/
https://ncbi.nlm.nih.gov/pubmed/16080782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051012
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