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The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca(2+)-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B
ALG-2 (apoptosis-linked gene 2) is a Ca(2+)-binding protein that belongs to the PEF (penta-EF-hand) protein family. Alix (ALG-2-interacting protein X)/AIP1 (ALG-2-interacting protein 1), one of its binding partners, interacts with TSG101 and CHMP4 (charged multivesicular body protein 4), which are c...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Portland Press Ltd.
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1276969/ https://ncbi.nlm.nih.gov/pubmed/16004603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050398 |
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