N-glycans of core2 β(1,6)-N-acetylglucosaminyltransferase-I (C2GnT-I) but not those of α(1,3)-fucosyltransferase-VII (FucT-VII) are required for the synthesis of functional P-selectin glycoprotein ligand-1 (PSGL-1): effects on P-, L- and E-selectin binding

C2GnT-I [core2 β(1,6)-N-acetyglucosaminyltransferase-I] and FucT-VII [α(1,3)-fucosyltransferase-VII] are the key enzymes for the biosynthesis of sialyl-Lewis x determinants on selectin ligands and therefore they represent good drug targets for the treatment of inflammatory disorders and other pathol...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Prorok-Hamon, Maëlle, Notel, Frédéric, Mathieu, Sylvie, Langlet, Claire, Fukuda, Minoru, El-Battari, Assou
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276950/
https://ncbi.nlm.nih.gov/pubmed/15926890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050344
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados