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Brown recluse spider (Loxosceles reclusa) venom phospholipase D (PLD) generates lysophosphatidic acid (LPA)

Envenomation by the brown recluse spider (Loxosceles reclusa) may cause local dermonecrosis and, rarely, coagulopathies, kidney failure and death. A venom phospholipase, SMaseD (sphingomyelinase D), is responsible for the pathological manifestations of envenomation. Recently, the recombinant SMaseD...

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Detalles Bibliográficos
Main Authors: Lee, Sangderk, Lynch, Kevin R.
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276930/
https://ncbi.nlm.nih.gov/pubmed/15926888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050043
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