Effects of nitric oxide donors on cybrids harbouring the mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) A3243G mitochondrial DNA mutation

Reactive nitrogen and oxygen species (O(2)(•−), H(2)O(2), NO(•) and ONOO(−)) have been strongly implicated in the pathophysiology of neurodegenerative and mitochondrial diseases. In the present study, we examined the effects of nitrosative and/or nitrative stress generated by DETA-NO {(Z)-1-[2-amino...

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Detalhes bibliográficos
Main Authors: Sandhu, Jagdeep K., Sodja, Caroline, Mcrae, Kevan, Li, Yan, Rippstein, Peter, Wei, Yau-Huei, Lach, Boleslaw, Lee, Fay, Bucurescu, Septimiu, Harper, Mary-Ellen, Sikorska, Marianna
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276916/
https://ncbi.nlm.nih.gov/pubmed/15969653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050272
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