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Dynamic force spectroscopy of parallel individual Mucin1–antibody bonds

We used atomic force microscopy to measure the binding forces between Mucin1 (MUC1) peptide and a single-chain variable fragment (scFv) antibody selected from a scFv library screened against MUC1. This binding interaction is central to the design of molecules used for targeted delivery of radioimmun...

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Detalhes bibliográficos
Main Authors: Sulchek, Todd A., Friddle, Raymond W., Langry, Kevin, Lau, Edmond Y., Albrecht, Huguette, Ratto, Timothy V., DeNardo, Sally J., Colvin, Michael E., Noy, Aleksandr
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276867/
https://ncbi.nlm.nih.gov/pubmed/16269547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505208102
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