Rapid Activation of Protein Tyrosine Kinase and Phospholipase C-γ2 and Increase in Cytosolic Free Calcium Are Required by Ehrlichia chaffeensis for Internalization and Growth in THP-1 Cells

Ehrlichia chaffeensis, a bacterium that cannot survive outside the eukaryotic cell, proliferates exclusively in human monocytes and macrophages. In this study, signaling events required for ehrlichial infection of human monocytic cell line THP-1 were characterized. Entry and proliferation of E. chaf...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Lin, Mingqun, Zhu, Michael X., Rikihisa, Yasuko
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127685/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11796624/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.2.889-898.2002
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