TP53 mutations in ovarian carcinomas from sporadic cases and carriers of two distinct BRCA1 founder mutations; relation to age at diagnosis and survival

BACKGROUND: Ovarian carcinomas from 30 BRCA1 germ-line carriers of two distinct high penetrant founder mutations, 20 carrying the 1675delA and 10 the 1135insA, and 100 sporadic cases were characterized for somatic mutations in the TP53 gene. We analyzed differences in relation to BRCA1 germline stat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kringen, Pedro, Wang, Yun, Dumeaux, Vanessa, Nesland, Jahn M, Kristensen, Gunnar, Borresen-Dale, Anne-Lise, Dorum, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276789/
https://ncbi.nlm.nih.gov/pubmed/16229746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-5-134
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados