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Onchocerca volvulus Glycolytic Enzyme Fructose-1,6-Bisphosphate Aldolase as a Target for a Protective Immune Response in Humans

To identify potential vaccine candidates for the prevention of infection with the filarial nematode Onchocerca volvulus, we screened an O. volvulus L3 stage cDNA library with sera from putatively immune (PI) subjects, and a prominent immunogenic clone of 1,184 nucleotides was identified. It containe...

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Publicado en:Infect Immun
Principais autores: McCarthy, James S., Wieseman, Moira, Tropea, Joe, Kaslow, David, Abraham, David, Lustigman, Sara, Tuan, Rocky, Guderian, Ronald H., Nutman, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2002
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11796620/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.2.851-858.2002
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