Staphylococcus aureus agr and sarA Functions Are Required for Invasive Infection but Not Inflammatory Responses in the Lung

Staphylococcus aureus strains lacking agr- and sarA-dependent gene products or specific MSCRAMM (microbial surface components recognizing adhesive matrix molecules) adhesins were compared for the ability to activate inflammatory responses in the lung. The mutants were evaluated for virulence in a mo...

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Autori principali: Heyer, Geoffrey, Saba, Shahryar, Adamo, Robert, Rush, William, Soong, Grace, Cheung, Ambrose, Prince, Alice
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC127645/
https://ncbi.nlm.nih.gov/pubmed/11748173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.1.127-133.2002
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