DNA Vaccine Combinations Expressing Either Tissue Plasminogen Activator Signal Sequence Fusion Proteins or Ubiquitin-Conjugated Antigens Induce Sustained Protective Immunity in a Mouse Model of Pulmonary Tuberculosis

DNA vaccination has emerged as a powerful approach in the search for a more efficacious vaccine against tuberculosis. In this study, we evaluated the effectiveness of immunizing with combinations of 10 different tuberculosis DNA vaccines that expressed mycobacterial proteins fused at the N terminus...

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Bibliografski detalji
Glavni autori: Delogu, Giovanni, Li, Amy, Repique, Charlene, Collins, Frank, Morris, Sheldon L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Microbial Immunity and Vaccines
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC127618/
https://ncbi.nlm.nih.gov/pubmed/11748195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.1.292-302.2002
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