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Investigating the SecY plug movement at the SecYEG translocation channel

Protein translocation occurs across the energy-conserving bacterial membrane at the SecYEG channel. The crystal structure of the channel has revealed a possible mechanism for gating and opening. This study evaluates the plug hypothesis using cysteine crosslink experiments in combination with various...

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Autores principales: Tam, Patrick C K, Maillard, Antoine P, Chan, Kenneth K Y, Duong, Franck
Formato: Artigo
Lenguaje:Inglês
Publicado: 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276166/
https://ncbi.nlm.nih.gov/pubmed/16148946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600804
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