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Cofilin expression induces cofilin-actin rod formation and disrupts synaptic structure and function in Aplysia synapses
Cofilin-actin rods are inclusion-like structures that are induced by certain chemical or physical stresses in cultured cells, and the rods formed in neurons are thought to be associated with neurodegeneration. Here, we cloned an Aplysia cofilin homolog and overexpressed it in cultured neurons. Overe...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1276089/ https://ncbi.nlm.nih.gov/pubmed/16247020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507675102 |
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