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Synergy between interstitial flow and VEGF directs capillary morphogenesis in vitro through a gradient amplification mechanism
Cell organization is largely orchestrated by extracellular gradients of morphogenetic proteins. VEGF, an essential factor for capillary formation, is stored in the extracellular matrix, but the mechanisms by which it and other matrix-bound morphogens are mobilized to form spatial gradients are poorl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1276047/ https://ncbi.nlm.nih.gov/pubmed/16249343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503681102 |
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