Mutations in the M4 domain of Torpedo californica acetylcholine receptor dramatically alter ion channel function.

Site-directed mutagenesis was used to mutate alpha Cys418 and beta Cys447 in the M4 domain of Torpedo californica acetylcholine receptor expressed in Xenopus laevis oocytes. The M4 region is a transmembrane domain thought to be located at the lipid-protein interface. By whole-cell voltage clamp anal...

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Sonraí Bibleagrafaíochta
Main Authors: Lee, Y H, Li, L, Lasalde, J, Rojas, L, McNamee, M, Ortiz-Miranda, S I, Pappone, P
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1994
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1275761/
https://ncbi.nlm.nih.gov/pubmed/7516721
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