Linkage Analysis of a Complex Pedigree with Severe Bipolar Disorder, Using a Markov Chain Monte Carlo Method

Recently developed algorithms permit nonparametric linkage analysis of large, complex pedigrees with multiple inbreeding loops. We have used one such algorithm, implemented in the package SimWalk2, to reanalyze previously published genome-screen data from a Costa Rican kindred segregating for severe...

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Huvudupphovsmän: Garner, Chad, McInnes, L. Alison, Service, Susan K., Spesny, Mitzi, Fournier, Eduardo, Leon, Pedro, Freimer, Nelson B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society of Human Genetics 2001
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1275626/
https://ncbi.nlm.nih.gov/pubmed/11222106
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