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Mutator Bacteria as a Risk Factor in Treatment of Infectious Diseases
We show in a gnotobiotic mouse model that, in addition to direct selection of antibiotic-resistant bacteria, some antibiotic treatments also select for mutator alleles. Because of these mutator alleles' high mutation rates, the initial treatment failure increases the probability of failures in...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC127494/ https://ncbi.nlm.nih.gov/pubmed/11850274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.3.863-865.2002 |
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