Comparison of Fractional Inhibitory Concentration Index with Response Surface Modeling for Characterization of In Vitro Interaction of Antifungals against Itraconazole-Susceptible and -Resistant Aspergillus fumigatus Isolates

Although the fractional inhibitory concentration (FIC) index is most frequently used to define or to describe drug interactions, it has some important disadvantages when used for drugs against filamentous fungi. This includes observer bias in the determination of the MIC and no agreement on the endp...

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Detalhes bibliográficos
Main Authors: Te Dorsthorst, D. T. A., Verweij, P. E., Meis, J. F. G. M., Punt, N. C., Mouton, J. W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127491/
https://ncbi.nlm.nih.gov/pubmed/11850251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.3.702-707.2002
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