Relationship between Chloroquine Toxicity and Iron Acquisition in Saccharomyces cerevisiae

Chloroquine is one of the most effective antimalarials, but resistance to it is becoming widespread. However, we do not fully understand either the drug's mode of action or the mechanism of resistance. In an effort to expand our understanding of the mechanism of action and resistance associated with...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Emerson, Lyndal R., Nau, Martin E., Martin, Rodger K., Kyle, Dennis E., Vahey, Maryanne, Wirth, Dyann F.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2002
Subjects:	Mechanisms of Action: Physiological Effects
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127479/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850263/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.787-796.2002
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