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Antibacterial Properties of Dermaseptin S4 Derivatives with In Vivo Activity

Derivatives of the cytotoxic peptide dermaseptin S4 have recently emerged as potential antimicrobial agents. Here, we report on the antibacterial properties of three derivatives with improved toxicity profiles: a 28-residues K(4)K(20)-S4 and two shorter versions, K(4)-S4(1-16) and K(4)-S4(1-13). The...

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Detalhes bibliográficos
Main Authors: Navon-Venezia, Shiri, Feder, Rina, Gaidukov, Leonid, Carmeli, Yehuda, Mor, Amram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127478/
https://ncbi.nlm.nih.gov/pubmed/11850249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.3.689-694.2002
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