Intrapulmonary Pharmacokinetics of Telithromycin, a New Ketolide, in Healthy Japanese Volunteers

The concentrations of telithromycin, a new ketolide antimicrobial agent, in alveolar macrophages (AMs) and bronchoalveolar epithelial lining fluid (ELF) were determined in order to investigate the transfer of the drug into target tissue, relative to plasma, following multiple oral doses of telithrom...

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Autores principales: Kadota, Jun-Ichi, Ishimatsu, Yuji, Iwashita, Tetsuji, Matsubara, Yuichi, Tomono, Kazunori, Tateno, Masao, Ishihara, Roza, Muller-Serieys, Claudette, Kohno, Shigeru
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC127464/
https://ncbi.nlm.nih.gov/pubmed/11850288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.3.917-921.2002
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