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Intrapulmonary Pharmacokinetics of Telithromycin, a New Ketolide, in Healthy Japanese Volunteers

The concentrations of telithromycin, a new ketolide antimicrobial agent, in alveolar macrophages (AMs) and bronchoalveolar epithelial lining fluid (ELF) were determined in order to investigate the transfer of the drug into target tissue, relative to plasma, following multiple oral doses of telithrom...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Kadota, Jun-Ichi, Ishimatsu, Yuji, Iwashita, Tetsuji, Matsubara, Yuichi, Tomono, Kazunori, Tateno, Masao, Ishihara, Roza, Muller-Serieys, Claudette, Kohno, Shigeru
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2002
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127464/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850288/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.917-921.2002
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