Antiviral Activities of MCC-478, a Novel and Specific Inhibitor of Hepatitis B Virus

MCC-478 is a newly synthesized 2-amino-6-arylthio-9-phosphonomethoxyethylpurine bis(2,2,2-trifluoroethyl) ester derivative. MCC-478 showed a substantially higher (ca. 80-fold) anti-hepatitis B virus (HBV) activity than that of lamivudine, despite no significant anti-human immunodeficiency virus acti...

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Detalhes bibliográficos
Main Authors: Kamiya, Naohiro, Kubota, Atsushi, Iwase, Yumiko, Sekiya, Kouichi, Ubasawa, Masaru, Yuasa, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127398/
https://ncbi.nlm.nih.gov/pubmed/12183240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.9.2872-2877.2002
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