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Alkoxyalkyl Esters of Cidofovir and Cyclic Cidofovir Exhibit Multiple-Log Enhancement of Antiviral Activity against Cytomegalovirus and Herpesvirus Replication In Vitro

The incidence of cytomegalovirus (CMV) retinitis is declining in AIDS patients but remains a significant clinical problem in patients with organ transplants and bone marrow transplants. Prophylaxis with ganciclovir (GCV) or valganciclovir reduces the incidence of CMV disease but may lead to the emer...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Beadle, James R., Hartline, Caroll, Aldern, Kathy A., Rodriguez, Natalie, Harden, Emma, Kern, Earl R., Hostetler, Karl Y.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127379/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121908/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2381-2386.2002
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