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Metagenomics for studying unculturable microorganisms: cutting the Gordian knot

More than 99% of prokaryotes in the environment cannot be cultured in the laboratory, a phenomenon that limits our understanding of microbial physiology, genetics, and community ecology. One way around this problem is metagenomics, the culture-independent cloning and analysis of microbial DNA extrac...

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Detalhes bibliográficos
Main Authors: Schloss, Patrick D, Handelsman, Jo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1273625/
https://ncbi.nlm.nih.gov/pubmed/16086859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2005-6-8-229
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