Sulfadoxine-Pyrimethamine Resistance in the Rodent Malaria Parasite Plasmodium chabaudi

We have studied resistance to sulfadoxine-pyrimethamine (S/P) in the rodent malaria parasite Plasmodium chabaudi. A stable S/P-resistant mutant, AS(50S/P), was selected by drug treatment of a clone, AS(PYR), already resistant to pyrimethamine. The sequences of the P. chabaudi dhfr and dhps genes wer...

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Bibliografiske detaljer
Main Authors: Hayton, Karen, Ranford-Cartwright, Lisa C., Walliker, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127344/
https://ncbi.nlm.nih.gov/pubmed/12121922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2482-2489.2002
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