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In Vivo Activity of Posaconazole against Mucor spp. in an Immunosuppressed-Mouse Model

The in vivo activities of posaconazole, itraconazole, and amphotericin B in neutropenic mice with zygomycosis were compared. The in vitro MICs of posaconazole and itraconazole for the strains of Mucor spp. used in this study ranged from 0.125 to 8 μg/ml and 0.25 to 8 μg/ml, respectively. The in vitr...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Sun, Qiu N., Najvar, Laura K., Bocanegra, Rosie, Loebenberg, David, Graybill, John R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127310/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12069997/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.7.2310-2312.2002
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