Resistance to Quinupristin-Dalfopristin Due to Mutation of L22 Ribosomal Protein in Staphylococcus aureus

The mechanism of resistance to the streptogramin antibiotics quinupristin and dalfopristin was studied in a Staphylococcus aureus clinical isolate selected under quinupristin-dalfopristin therapy, in four derivatives of S. aureus RN4220 selected in vitro, and in a mutant selected in a model of rabbi...

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Bibliographic Details
Main Authors: Malbruny, Brigitte, Canu, Annie, Bozdogan, Bülent, Fantin, Bruno, Zarrouk, Virginie, Dutka-Malen, Sylvie, Feger, Celine, Leclercq, Roland
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC127308/
https://ncbi.nlm.nih.gov/pubmed/12069975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.7.2200-2207.2002
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