Genetic and Functional Characterization of the Escherichia coli BarA-UvrY Two-Component System: Point Mutations in the HAMP Linker of the BarA Sensor Give a Dominant-Negative Phenotype

The BarA-UvrY two-component system family is strongly associated with virulence but is poorly understood at the molecular level. During our attempts to complement a barA deletion mutant, we consistently generated various mutated BarA proteins. We reasoned that characterization of the mutants would h...

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Bibliografiska uppgifter
Huvudupphovsmän: Tomenius, Henrik, Pernestig, Anna-Karin, Méndez-Catalá, Claudia F., Georgellis, Dimitris, Normark, Staffan, Melefors, Öjar
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2005
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1273000/
https://ncbi.nlm.nih.gov/pubmed/16237014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.21.7317-7324.2005
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