Efficacy of β-Lactams for Treating Experimentally Induced Pneumonia Due to a Carbapenem-Hydrolyzing Metallo-β-Lactamase-Producing Strain of Pseudomonas aeruginosa

A rat pneumonia model was established with a Pseudomonas aeruginosa strain that produced the plasmid-encoded metallocarbapenemase VIM-2. A significant decrease in lung bacterial titers was observed when imipenem, cefepime, ceftazidime, and piperacillin-tazobactam were given at the highest doses reco...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Bellais, Samuel, Mimoz, Olivier, Léotard, Sophie, Jacolot, Anne, Petitjean, Olivier, Nordmann, Patrice
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127240/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019134/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.2032-2034.2002
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