Impact of N-Chlorotaurine on Viability and Production of Secreted Aspartyl Proteinases of Candida spp.

N-Chlorotaurine, an endogenous long-lived oxidant, demonstrated fungicidal activity against Candida spp. and a postantifungal effect. Secreted aspartyl proteinases, important fungal virulence factors, proved to be a first target of impact. These results provide support for the topical application of...

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Detalhes bibliográficos
Main Authors: Nagl, Markus, Gruber, Andreas, Fuchs, Anita, Lell, Claudia P., Lemberger, Eva-Maria, Borg-von Zepelin, Margarete, Würzner, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127226/
https://ncbi.nlm.nih.gov/pubmed/12019124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.1996-1999.2002
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