TEM-71, a Novel Plasmid-Encoded, Extended-Spectrum β-Lactamase Produced by a Clinical Isolate of Klebsiella pneumoniae

TEM-71, a novel extended-spectrum β-lactamase from a Klebsiella pneumoniae clinical isolate, had an isoelectric point of 6.0 and a substrate profile showing preferential hydrolysis of cefotaxime over ceftazidime. It differed from TEM-1 by two substitutions, Gly238Ser and Glu240Lys, and was under the...

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Bibliographic Details
Main Authors: Rasheed, J. Kamile, Anderson, Gregory J., Queenan, Anne Marie, Biddle, James W., Oliver, Antonio, Jacoby, George A., Bush, Karen, Tenover, Fred C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC127224/
https://ncbi.nlm.nih.gov/pubmed/12019125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.2000-2003.2002
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