Detection of a Variant Metallo-β-Lactamase, IMP-10, from Two Unrelated Strains of Pseudomonas aeruginosa and an Alcaligenes xylosoxidans Strain

The gene bla(IMP-10) of a variant metallo-β-lactamase, IMP-10, had a single base replacement of G by T at nucleotide 145, which led to an amino acid alteration of Val49 to Phe compared to the IMP-1 enzyme, indicating that IMP-10 was a point mutation derivative of IMP-1. Highly purified enzymes revea...

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Bibliographische Detailangaben
Hauptverfasser: Iyobe, Shizuko, Kusadokoro, Haruko, Takahashi, Ayako, Yomoda, Sachie, Okubo, Toyoji, Nakamura, Akio, O'Hara, Koji
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127220/
https://ncbi.nlm.nih.gov/pubmed/12019129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.2014-2016.2002
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