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Effects of Metronidazole, Tetracycline, and Bismuth-Metronidazole-Tetracycline Triple Therapy in the Helicobacter pylori SS1 Mouse Model after 1 Day of Dosing: Development of an H. pylori Lead Selection Model

We evaluated the effect of optimized doses and dosing schedules of metronidazole, tetracycline, and bismuth-metronidazole-tetracycline (BMT) triple therapy with only 1 day of dosing on Helicobacter pylori SS1 titers in a mouse model. A reduction of bacterial titers was observable with 22.5 and 112.5...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Sizemore, Christine F., Quispe, Joel D., Amsler, Karen M., Modzelewski, Todd C., Merrill, Jayson J., Stevenson, D. Andrew, Foster, Lorie A., Slee, Andrew M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2002
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127199/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959579/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.5.1435-1440.2002
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