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Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate
Induction of p21 in senescent human fibroblasts plays a key role in the inactivation of cyclin-dependent kinases and the resulting irreversible growth arrest in the early stages of cell senescence. We found that RNA-binding proteins are critical regulators of p21 during senescence. Two RNA-binding p...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1271759/ https://ncbi.nlm.nih.gov/pubmed/14726956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600052 |
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